Disposition - disappearance cases of the body of a homicide victim create "challenges" in the criminal justice process. However, although these cases are characterized as rare, they do exist, they can be solved and the perpetrator convicted - even without the most important piece of the puzzle. The subject under study in this thesis has as its main purpose to highlight this relatively rare, for the legal annals, topic, taking into account the lack of research literature, especially in Greece and Cyprus. In order to capture, as comprehensively as possible, this subject, this Master's Thesis consists of chapters and the data mentioned is result from bibliographic research. Particular emphasis is placed, in the Corpus Delicti rule, on the false confessions of suspects as well as the precarious nature of witness statements in the light of circumstantial evidence. This is followed by information relating to forensic and criminological investigation, the types of disposal of a victim's body and the characteristics of those involved. At the same time, through the discussion of important aspects of the research topic, the present study completes its theoretical part, emphasizing on the dismantling of the "no body, no murder" rule. Following the flow of the chapters, real cases are listed that occupied the common and not only opinion, in Greece and abroad, in which until today, no part of the body of the victims has been recovered. The characteristics of the cases differ based on whether the homicide is related to financial motivation, domestic violence, etc. In these cases, the facts are stated, the challenges that emerged from each type of case are examined, culminating in the Judicial crisis.